Investigación clínica
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Application of Comprehensive Genomic Profiling-Based Next-Generation Sequencing Assay to Improve Cancer Care in a Developing Country
Purpose Identifying actionable oncogenic mutations have changed the therapeutic landscape in different types of tumors. This study investigated the utility of comprehensive genomic profiling (CGP), a hybrid capture-based ...2023 -
Importancia del conocimiento anatómico del espacio extraperitoneal y su utilidad en los abordajes quirúrgicos
ResumenIntroducción.El espacio extraperitoneal, se define como el segmento topográfico ubicado entre el peritoneo parietal internamente y la fascia transversalis externamente. Como resultado del desarrollo y consolidación ...2023 -
Valentino's syndrome: Simulation of acute appendicitis in the context of peptic ulcer perforation. Case report and literature review
Introduction and importance Abdominal pain (AP) is one of the main reasons for consultation in the emergency department worldwide. The causes of AP are gathered in a broad group of pathologies whose incidence and prevalence ...2023 -
Endovascular approach of hepatic artery pseudoaneurysm after Whipple procedure: Case report and literature review
Introduction and importance Pseudoaneurysms after pancreatoduodenectomy are an uncommon complication, but they are associated with life-threatening outcomes in up to 50 % due to the development of postoperative bleeding. ...2023 -
Postoperative and Pathological Outcomes of CROSS and FLOT as Neoadjuvant Therapy for Esophageal and Junctional Adenocarcinoma An International Cohort Study From the Oesophagogastric Anastomosis Audit (OGAA)
Objective: This study aimed to compare the postoperative and pathological outcomes between carboplatin, paclitaxel, radiotherapy (CROSS) and 5-FU, leucovorine, oxaliplatin and docetaxel (FLOT) in esophageal adenocarcinoma ...2023 -
Laparoscopic cholecystectomy in super elderly (>90 years of age): safety and outcomes
Background Nonagenarian patients are an age group in progressive growth. In this age group, indications for surgical procedures, including cholecystectomy, will be increasingly frequent, as biliary pathology and its ...2023 -
State of the art in subtotal cholecystectomy: An overview
Introduction: Subtotal cholecystectomy is a type of surgical bail-out procedure indicated when facing difficult laparoscopic cholecystectomy due to not reaching the critical view of safety, inadequate identification of the ...2023 -
Severe Acute Cholecystitis (Tokyo III) in High-Risk Patients: Should Cholecystectomy Be Preferred over Percutaneous Drainage?
Current guidelines advise the use of less aggressive procedures for the solution of cholecystitis in high risk patients. However, recent literature has shown better results in those patients managed with laparoscopic ...2023 -
A new non-invasive index for the prediction of endotracheal intubation in patients with SARS COVID-19 infection, in the emergency department, pilot study
Background In the current context of the SARS COVID-19 pandemic, where the main cause of death is respiratory failure, and since early recognition would allow timely measures to be implemented and probably improve outcomes, ...2023 -
Tratamiento agudo de la migraña durante el embarazo
INTRODUCCIÓN La migraña es una condición médica prevalente y altamente discapacitante. Por lo general, durante el embarazo hay una reducción de los síntomas migrañosos, sin embargo, en ocasiones la sintomatología puede ...2023 -
A hood shield reduces postdoffing contamination during simulated COVID-19 airway management: an exploratory, simulation-based randomized study
Purpose SARS-CoV-2 poses a significant occupational health threat to health care workers performing aerosol-generating medical procedures, with a threefold increased risk of a positive test and predicted infection compared ...2023 -
Why do patients with antiphospholipid syndrome bleed? A clinical paradox
Although worldwide-known criteria of antiphospholipid syndrome include thrombotic and obstetric events, a moderate number of patients manifest with bleeding episodes during course of the disease, which is typically attributed ...2023 -
Periprosthetic fracture management of the proximal femur
The most common periprosthetic fractures occur around the hip. The most widely used classification is the Vancouver classification, and management requires careful planning and skill in both arthroplasty and fracture ...2023 -
Resultados clínicos de una cohorte de pacientes con síndrome de intestino irritable tratados con probióticos multicepa
Introducción. Dentro de las alternativas para el tratamiento del síndrome de intestino irritable se han propuesto los probióticos, que contribuyen al control del dolor y de la distensión abdominal. La presente investigación ...2023 -
Appendiceal Phlegmon as an intraoperative finding: A retrospective analysis
Background Emergency procedures due to acute surgical abdomen correspond to a great part of emergency surgeries. Appendicitis is the most common abdominal surgical emergency in the world. Intraoperative findings ...2023 -
Intermediate Risk of Choledocholithiasis: Are we on the right path?
The risk of choledocholithiasis should be assessed in every patient undergoing cholecystectomy to define the next step. The American Society for Gastrointestinal Endoscopy proposed a stratified predictor scale of ...2023 -
Rapidly progressive glomerulonephritis secondary to anti-GBM disease associated with MPO-ANCA: a case report
Abstract Background Anti-glomerular basement membrane (GBM) disease and ANCA-associated vasculitis (AAV) diseases are rare. It is associated with variable renal manifestations and increased mortality, thus requiring early ...2023 -
Giant Hydatid Cyst with Diaphragmatic, Pericardial, and Hepatic Involvement: Use of Extracorporeal Circulation for Major Liver Resection: A Case Report and Literature Review.
BACKGROUND: Echinococcosis is a zoonosis caused by the echinococcus microorganism, a parasite with 6 described species in the literature, the main one in humans being Echinococcus granulosus. Transmission is via the ...2023 -
Outcomes after Frey's procedure for chronic pancreatitis: A 8-year single-center experience in Colombia
Background: Chronic pancreatitis is an inflammatory disease characterized by irreversible morphological changes due to chronic pancreatic fibrosis. The treatment goals are to relieve pain, preserve function, and prevent ...2022-12 -
Agreement between an Early-Onset Neonatal Sepsis Risk Calculator and the Colombian Clinical Practice Guideline in Three Tertiary-Care Centers in Bogotá, Colombia
Objective: Clinical practice guidelines (CPG) worldwide help steer the management of early-onset neonatal sepsis (EONS). These documents typically discourage the use of risk assessment tools. However, prior work has shown ...2023-01
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